External quality assessment of point-of-care International Normalized Ratio (INR) testing in Europe

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External quality assessment of point-of-care International Normalized Ratio (INR) testing in Europe.

BACKGROUND Point-of-care testing (POCT) of prothrombin time, expressed as International Normalized Ratio (INR), is widely used to monitor patients in oral anticoagulation treatment. Guidelines recommend that POCT users should participate in an external quality assessment (EQA) scheme whenever available. The aim of this study was to investigate which European countries provide EQA for POCT INR a...

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International Normalized Ratio ( Inr )

Prothrombin time can be measured roughly on whole blood as in neonates, but is more commonly measured from plasma. Blood is taken into a vacutainer containing liquid citrate. Citrate acts as an anticoagulant by consuming all the calcium in the sample. The blood is mixed and centrifuged to separate blood cells from the plasma. The plasma is placed in a coagulation machine which takes a sample of...

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Preparation of control blood for external quality assessment of point-of-care international normalized ratio testing in the Netherlands.

OBJECTIVES The aim of this study was to prepare control blood for an external quality assessment scheme (EQAS) for international normalized ratio (INR) point-of-care testing (POCT) in the Netherlands and to assess the performance of the participants. METHODS Control blood was prepared from dialyzed pooled patient plasma and washed human erythrocytes. Samples of control blood were mailed to pa...

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Quality assessment of CoaguChek point-of-care international normalized ratio monitors: a note of caution.

1. Danpure CJ. Primary hyperoxaluria. In: Scriver CR, Beaudet AL, Sly WS, Valle D, eds. The Metabolic and Molecular Bases of Inherited Disease. New York: McGraw-Hill, 2001:3323–67. 2. van Woerden CS, Groothoff JW, Wanders RJ, Davin JC, Wijburg FA. Primary hyperoxaluria type 1 in The Netherlands: prevalence and outcome. Nephrol Dial Transplant 2003;18:273–9. 3. van Woerden CS, Groothoff JW, Wijb...

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Point-of-care testing of the international normalized ratio in patients with antiphospholipid antibodies.

Antiphospholipid antibodies can influence the results of clotting tests in a subset of patients, which can be a major obstacle in monitoring warfarin. The aim was to determine if point-of-care testing of the International Normalized Ratio (INR) is influenced by antiphospholipid antibodies. We compared 59 patients receiving warfarin for a diagnosis of antiphospholipid antibody syndrome (APS) to ...

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ژورنال

عنوان ژورنال: Clinical Chemistry and Laboratory Medicine

سال: 2012

ISSN: 1437-4331,1434-6621

DOI: 10.1515/cclm.2011.719